BioMedical Interventions

Biomedical treatment in regards to autism spectrum disorders is just that a systemic examination of the entire child’s physical internal and external environment. Most physicians and practitioners using biomedical treatments consider the symptoms of autism overt indicators of deeper underlying conditions. These treatments are based on the philosophy, which involves trying to treat the underlying causes of the symptoms of autism, based on medical testing, scientific research, and clinical experience, with an emphasis on nutritional interventions.

Biomedical treatments will not help every child, but they have helped thousands of children improve, sometimes dramatically.

Summary of Biomedical Treatments for Autism By James B. Adams, Ph.D.

This document is intended to provide a simple summary of the major biomedical treatments available to help children and adults with autism/Asperger’s. Biomedical treatments will not help every child, but they have helped thousands of children improve, sometimes dramatically. This summary is primarily based on the excellent book “Autism: Effective Biomedical Treatments” by Jon Pangborn, Ph.D., and Sidney Baker, MD,. published by the Autism Research Institute. That book provides much more depth on the testing and treatments which are briefly summarized in this document. Another
good source of information is “Children with Starving Brains,” by Jaquelyn McCandless, MD. After reading this document, it is highly recommended that you go to those sources for more information. This summary generally follows the DAN! philosophy, which involves trying to treat the underlying causes of the symptoms of autism, based on medical testing, scientific research, and clinical experience, with an emphasis on nutritional interventions. Many of the DAN! treatments have been found by listening to parents and physicians. ARI Survey of Parent Ratings of Treatment Efficacy Most of the treatments listed on the following pages were evaluated as part of the Autism Research Institute (ARI) survey of over 23,000 parents on their opinion of the effectiveness of various treatments for children with autism. For a full copy of the latest ARI Survey, see the last page.

Other Interventions:
Behavioral interventions, such as Applied Behavior Analysis (ABA), can also be very helpful to children with autism, and are recommended to be used in conjunction with biomedical treatments. Similarly, speech therapy, sensory integration, physical therapy, occupational therapy, and a good educational program can be very important. Finally, social interventions (such as Relationship Development Intervention) and social groups can be very helpful in building social relationships and skills. Biomedical therapy may help improve the efficacy of these other interventions, by improving brain and body health and making it easier for the child to learn.

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Diagnosis Autism: Now What? A Simplified Biomedical Approach by Dr Rossignol

Dan Rossignol, MD, FAAFP received his Doctorate of Medicine at the Medical College of Virginia and completed his residency in family medicine at the University of Virginia
(UVa). He is a former clinical assistant professor of family medicine at UVa and is currently a staff physician at the International Child Development Resource Center. He is the father of two children with autism. He has authored several papers including two on the use of HBOT in autism, one on the use of urinary porphyrins in autism, and another on mitochondrial dysfunction in autism. He is a medical advisor to the International Hyperbarics Association and USAAA, and is currently involved in research to find treatments for inflammation, oxidative stress, gastrointestinal problems and
heavy metal toxicity in autism.

In 2002, my older son, Isaiah, was diagnosed with autism. At the time I had been practicing as a family physician for about five years. Prior to his diagnosis, Isaiah loved to get down on the floor and spin objects, and I thought it was cool, so I helped him. He
also used to shake his hands back and forth in the air for hours. When I tried to shake my hands like him, I tired out in a couple of minutes. I couldn’t figure out how he could do it for hours! He had a significant speech delay and walked very late. However, despite all of these problems, I did not have a CLUE that he had autism. I remember when my wife and I went to his psychological evaluation to determine what was wrong with him. He was evaluated by a pediatric neurologist and several psychologists, and we spent the morning with him during the testing. We were then told to go to lunch while
the team met to determine a diagnosis. I remember as we sat in McDonalds
eating French fries and cheeseburgers that my wife and I discussed that maybe
the team would say he had “autistic tendencies.” It was quite a shock to us when Isaiah was actually diagnosed with autism! For the first year after his diagnosis, my wife started looking into biomedical treatments, which I considered “quackery.” I remember asking some pediatric neurologists about the glutenfree/casein-free (GF/CF) diet and being
told that NO evidence existed in the medical literature as to whether or not
this diet worked.

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Randomized, Placebo-Controlled Trial of Methyl B12 for Children with Autism

Abstract Objective: Children with autism spectrum disorder (ASD) have been reported to have reduced ability to methylate DNA and elevated markers of oxidative stress. We sought to determine if methyl B12, a key metabolic cofactor for cellular methylation reactions and antioxidant defense, could improve symptoms of ASD. Methods: A total of 57 children with ASD…

Small study finds B12 injections ease autism symptoms in some children

Carefully controlled study provides evidence that methyl B12 can ease autism in a subgroup of children with the disorder March 23, 2016 In a small but carefully controlled study, regular injections of methyl B12 produced an overall improvement in autism symptoms in some children who have the disorder. The researchers found that the behavior improvement…

Autoimmune and gastrointestinal dysfunctions

Autoimmune and gastrointestinal dysfunctions: does a subset of children with autism reveal a broader connection?   Abstract A large number of autoimmune disorders have a gastrointestinal (GI) dysfunction component that may interplay with genetic, hormonal, environmental and/or stress factors. This narrarive review investigates possible links between autism, immune system abnormalities and GI symptoms in a…

Identification and Treatment of Pathophysiological Comorbidities of Autism Spectrum Disorder to Achieve Optimal Outcomes

Abstract Despite the fact that the prevalence of autism spectrum disorder (ASD) continues to rise, no effective medical treatments have become standard of care. In this paper we review some of the pathophysiological abnormalities associated with ASD and their potential associated treatments. Overall, there is evidence for some children with ASD being affected by seizure…

Environmental Toxicants and Autism Spectrum Disorder By Daniel A. Rossignol, MDRichard E. Frye, MD, PhD

Autism spectrum disorder (ASD) is a neurodevelopmental disorder defined by behavioral observations and characterized by core impairments in speech and social interaction along with restricted and repetitive patterns of behaviors. Many children with ASD have additional behavioral impairments, including inattention, aggression, and hyperactivity. The prevalence of ASD in the US is estimated to be 1…

Dietary Interventions for Autism

A Randomised, Controlled Study of Dietary Intervention in Autistic Syndromes A.M. Knivsberg,K.L. Reichelt,T. HØien &M. NØdland Pages 251-261 | Published online: 02 Dec 2013 Download citation Abstract Impaired social interaction, communication and imaginative skills characterize autistic syndromes. In these syndromes urinary peptide abnormalities, derived from gluten, gliadin, and casein, are reported. They reflect processes with…

Leaky Gut and Autism

Are ‘leaky gut’ and behavior associated with gluten and dairy containing diet in children with autism spectrum disorders? Fernando Navarro,Deborah A Pearson,Nicole Fatheree,Rosleen Mansour,S Shahrukh Hashmi &J Marc Rhoads Pages 177-185 | Published online: 12 Feb 2014 Abstract Objectives Studies have suggested a link between diet and behavior in children with autism spectrum disorders (ASDs). Parental…

Gastrointestinal Issues in Autism

Autism and GI Disorders. … Gastrointestinal (GI) disorders are among the most common medical conditions associated with autism. These issues range from chronic constipation or diarrhea to irritable and inflammatory bowel conditions. They can affect persons of any age. Autoimmune and gastrointestinal dysfunctions: does a subset of children with autism reveal a broader connection? A large number of autoimmune…

Environment and Toxicity

Genes, ozone and autism Increased risk for autism when genetic variation and air pollution meet Sam Sholtis  June 22, 2017 UNIVERSITY PARK, Pa. — A new analysis shows that individuals with high levels of genetic variation and elevated exposure to ozone in the environment are at an even higher risk for developing autism than would be…

BioMedical Interventions

What are biomedical interventions? Emerging view of autism states with evidence to many bio markers that autism is a medical disorder. Many autistic individuals exhibit autistic behaviors due to many medical conditions. Biomedical intervention is referred to a group of interventions to help stop or atleast reduce the symptoms considered as biomedical problems such as…